The history of the Karamadai Ranganathar Temple is deeply rooted in local legends and regional lore. While precise historical records are scarce, it is believed that the temple dates back several centuries. The temple has received patronage from various dynasties ruling the region, including the Cholas and the Vijayanagara Empire, evident in its architectural styles and inscriptions. Over time, the temple has undergone several renovations and expansions, with contributions from local communities and philanthropists. The temple's significance grew due to its association with Vaishnavite saints and the propagation of their teachings. Today, the temple stands as a testament to the enduring faith and cultural heritage of the region, preserving its rich history and spiritual traditions.